Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348606 | 0.74 | MAOA (0.38) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| SCHEMBL30804593 | 0.74 | MAOA (0.38) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| SCHEMBL1173038 | 0.71 | IDO1 (0.34) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| Water SCHEMBL4797113 | 0.69 | IDO1 (0.33) | LMNAIDO1 | |
| SCHEMBL1886110 | 0.69 | MEN1 (0.40) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| SCHEMBL29056418 | 0.66 | IDO1 (0.33) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| SCHEMBL29593696 | 0.66 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL5568782 | 0.66 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL11018753 | 0.66 | IDO1 (0.31) | IDO1 | |
| SCHEMBL7335323 | 0.64 | MAPT (0.39) | KDM4EMEN1APAF1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125658-A1 | 4,5,11,11A-TETRAHYDRO-1H,6H-OXAZOLO[3',4':1,6]PYRIDO[3,4-B]INDOL-3-ONE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008101824-A1 | IMIDAZO[1',5':1,6] PYRIDO[3,4-B]INDOLES DERIVATIVES AND THERAPEUTICAL USE THEREOF | FOURTILLAN (FR) | 2008-08-28 | — | — | WO | disclosed |