Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607966 | 0.91 | KCNA3 (0.50) | KCNA3ALDH1A1TAAR1RECQLHTR1A | |
| SCHEMBL14778910 | 0.90 | PARL (0.47) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1109820 | 0.89 | DRD2 (0.50) | KCNA3DRD2DRD4DRD3CA12 | |
| SCHEMBL5945104 | 0.86 | PARL (0.47) | KCNA3ALDH1A1CA12CA1CA2 | |
| SCHEMBL14779172 | 0.84 | PARL (0.46) | KCNA3ALDH1A1CA12CA1CA2 | |
| SCHEMBL14779590 | 0.84 | PARL (0.46) | KCNA3ALDH1A1CA12CA1CA2 | |
| SCHEMBL3449015 | 0.82 | PARL (0.50) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL11274857 | 0.81 | TDP1 (0.41) | KCNA3ALDH1A1CA1CA2KMT2A | |
| SCHEMBL4685853 | 0.81 | PARL (0.43) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1395593 | 0.80 | CA12 (0.55) | DRD2DRD4DRD3ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |