SCHEMBL473986

SCHEMBL473986

COC(=O)CC1CCNCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.45
GABRA5 P31644 3/20 0.44
GABRB2 P47870 3/20 0.44
SLC6A1 P30531 2/20 0.44
SLC6A12 P48065 2/20 0.44
SLC6A11 P48066 2/20 0.44
SLC6A13 Q9NSD5 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRR1 P24046 1/20 0.44
BRD4 O60885 1/20 0.43
ALOX15 P16050 2/20 0.42
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
TSHR P16473 3/20 0.40
ANPEP P15144 1/20 0.39
ERAP2 Q6P179 1/20 0.39
CPN1 P15169 1/20 0.38
CPB2 Q96IY4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL662153 0.98 EPHX1 (0.44) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL15073379 0.89 BRD4 (0.39) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL15054802 0.89 BRD4 (0.39) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL12571547 0.88 SLC6A1 (0.60) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL853499 0.88 SLC6A1 (0.60) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL12571551 0.88 SLC6A1 (0.60) EPHX1GABRA5GABRB2SLC6A1SLC6A12
SCHEMBL8790494 0.87 BRD4 (0.45) EPHX1GABRA5GABRB2SLC6A1SLC6A12
Hydrochloric Acid SCHEMBL1966822 0.86 SLC6A1 (0.58) EPHX1GABRA5GABRB2SLC6A1SLC6A12
Hydrochloric Acid SCHEMBL1970167 0.86 SLC6A1 (0.58) EPHX1GABRA5GABRB2SLC6A1SLC6A12
Hydrochloric Acid SCHEMBL1966820 0.86 SLC6A1 (0.58) EPHX1GABRA5GABRB2SLC6A1SLC6A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
CN-118271235-A Quick detection method and detection device for dithiocarbamic acid ester pesticides in agricultural products 广州科技贸易职业学院 2024-07-02 CN claimed
EP-2470508-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2012-07-04 EP claimed
WO-2011025541-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2011-03-03 WO claimed
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN disclosed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
EP-4713018-A1 TRANSFECTION COMPOSITIONS SUITABLE FOR PRODUCING A BIOLOGICAL PRODUCT PolyPlus Transfection (FR) 2026-03-25 EP disclosed
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2026-02-12 US disclosed
EP-4681715-A2 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-4076450-B1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS INC (US) 2025-12-10 EP disclosed
US-12486290-B2 Isoindolinone and indazole compounds for the degradation of EGFR C4 THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
US-5866592-A Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same NIPPON STEEL CORPORATION (JP) 1999-02-02 US disclosed
EP-0852225-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND MEDICINAL PREPARATIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT NIPPON STEEL CORPORATION (JP) 1998-07-08 EP disclosed
EP-0815103-A1 TRYPSIN AND THROMBIN INHIBITORS Novartis AG (CH) 1998-01-07 EP disclosed
US-5700801-A ANTIINFLAMMATORY AGENTS, BONE DISORDERS KARL THOMAE, GMBH (DE) 1997-12-23 US disclosed
EP-0800516-A1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORPORATION (JP) 1997-10-15 EP disclosed
WO-1996029327-A1 TRYPSIN AND THROMBIN INHIBITORS NOVARTIS AG (CH) 1996-09-26 WO disclosed
WO-1996020172-A1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORPORATION (JP) 1996-07-04 WO disclosed
EP-0638553-A1 Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs Dr. Karl Thomae GmbH (DE) 1995-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486290-B2 Isoindolinone and indazole compounds for the degradation of EGFR EGFR, ERBB2, ERBB3 EPHX1 3266/4885GABRA5 1997/4885GABRB2 2626/4885
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto HTR2C, HTR1A, HTR2A EPHX1 1618/4885GABRA5 319/4885GABRB2 205/4885
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR EGFR, ERBB2, ERBB3 EPHX1 3291/4885GABRA5 891/4885GABRB2 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.