Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473986 | 0.87 | EPHX1 (0.45) | BRD4EPHX1HTR4SLC6A1GABRA5 | |
| Hydrochloric Acid SCHEMBL662153 | 0.85 | EPHX1 (0.44) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL8791493 | 0.80 | SLC6A12 (0.56) | EPHX1SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL15054802 | 0.77 | BRD4 (0.39) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL15073379 | 0.77 | BRD4 (0.39) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL853499 | 0.76 | SLC6A1 (0.60) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL12571551 | 0.76 | SLC6A1 (0.60) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL12571547 | 0.76 | SLC6A1 (0.60) | BRD4EPHX1SLC6A1GABRA5GABRB2 | |
| SCHEMBL8791466 | 0.76 | GLA (0.51) | L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1966822 | 0.75 | SLC6A1 (0.58) | BRD4EPHX1SLC6A1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |