Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737116 | 0.89 | MAPT (0.50) | MEN1KMT2AHTTPTGDR2NPC1 | |
| SCHEMBL3550162 | 0.82 | HDAC2 (0.54) | MEN1KMT2AHTTPTGDR2 | |
| SCHEMBL6840365 | 0.77 | KDM5A (0.47) | NPC1RAB9AHSD17B10 | |
| SCHEMBL25402995 | 0.76 | SMN1; SMN2 (0.48) | MEN1KMT2APTGDR2SMN1; SMN2HSD17B10 | |
| SCHEMBL4740073 | 0.75 | PDGFRB (0.49) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30585029 | 0.74 | PTGER4 (0.46) | — | |
| SCHEMBL3556891 | 0.73 | HDAC2 (0.61) | MEN1KMT2AHTT | |
| SCHEMBL19538829 | 0.73 | MAPT (0.61) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL5767415 | 0.72 | P2RX7 (0.48) | MEN1KMT2APTGDR2RAB9AMAPT | |
| SCHEMBL23632217 | 0.72 | AGTR1 (0.50) | NPC1RAB9ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089436-A2 | CRYSTALLINE FORMS OF HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089436-A2 | CRYSTALLINE FORMS OF HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2008-07-24 | — | — | WO | disclosed |