Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | CD74 | P04233 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401651 | 0.90 | THRB (0.53) | CD74MIFTP53DRD2TBXA2R | |
| SCHEMBL25403100 | 0.89 | POLB (0.46) | CD74MIFALDH1A1MEN1KMT2A | |
| SCHEMBL25402742 | 0.89 | FAAH (0.50) | CD74MIFALDH1A1KMT2AGAA | |
| SCHEMBL25402366 | 0.89 | HDAC6 (0.49) | MEN1KMT2AGAARAB9ADRD2 | |
| SCHEMBL25402905 | 0.89 | GAA (0.49) | TSHRMEN1KMT2ATP53GAA | |
| SCHEMBL12706998 | 0.88 | CA1 (0.47) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL25403732 | 0.88 | TP53 (0.47) | HPGDMEN1KMT2ATP53GAA | |
| SCHEMBL25401830 | 0.87 | CYP19A1 (0.50) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL25399737 | 0.87 | CD74 (0.48) | CD74MIFMEN1KMT2AADORA3 | |
| SCHEMBL25403016 | 0.87 | MRGPRX4 (0.46) | CD74MIFALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197369-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SOOKMYUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-06-19 | — | — | US | disclosed |
| EP-4494640-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Sookmyung Women's University Industry-Academic Cooperation Foundation (KR) | 2025-01-22 | — | — | EP | disclosed |
| CN-119212701-A | Novel histone deacetylase heterocycle inhibitor and pharmaceutical composition containing the same | 淑明女子大学校 产学协力团 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023177250-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 숙명여자대학교산학협력단 | 2023-09-21 | — | — | WO | disclosed |
| US-8383662-B2 | Bicyclic heteroaryl compounds | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-8383662-B2 | Bicyclic heteroaryl compounds | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-04-07 | — | — | US | disclosed |
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-04-07 | — | — | US | disclosed |
| US-7825261-B2 | Indazole compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2010-11-02 | — | — | US | disclosed |
| US-7825261-B2 | Indazole compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2010-11-02 | — | — | US | disclosed |
| WO-2008070599-A1 | INDAZOLE COMPOUNDS | SUN CHUNG-MING (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20080132501-A1 | INDAZOLE COMPOUNDS | NATIONAL TAIWAN UNIVERSITY (TW) | 2008-06-05 | — | — | US | disclosed |
| US-20080132501-A1 | INDAZOLE COMPOUNDS | NATIONAL TAIWAN UNIVERSITY (TW) | 2008-06-05 | — | — | US | disclosed |
| EP-1615636-A1 | BICYCLIC COMPOUNDS AS NR2B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089366-A1 | BICYCLIC COMPOUNDS AS NR2B RECEPTOR ANTAGONISTS | PFIZER JAPAN, INC. (JP) | 2004-10-21 | — | — | WO | disclosed |
| US-20040204409-A1 | Bicyclic compounds as NR2B receptor antagonists | ANDO KAZUO (JP) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197369-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HDAC1, HDAC6, HDAC5 | P2RX7 3939/4885CFTR 1794/4885FGFR1 612/4885 |
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | SDHA, CYP2F1, PAICS | P2RX7 4432/4885CFTR 3749/4885FGFR1 814/4885 |
| US-20080132501-A1 | INDAZOLE COMPOUNDS | CYP1B1, IDH3B, IDH2 | P2RX7 3105/4885CFTR 1068/4885FGFR1 657/4885 |
| US-20040204409-A1 | Bicyclic compounds as NR2B receptor antagonists | GRIN1, GRIN2B, GRIN2A | P2RX7 137/4885CFTR 3524/4885FGFR1 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.