SCHEMBL4740141 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.38

▸	TLR2	O60603	2/20	0.37

▸	CA1	P00915	1/20	0.36

▸	CA2	P00918	1/20	0.36

▸	CASP3	P42574	2/20	0.35

▸	FABP5	Q01469	3/20	0.35

▸	FABP7	O15540	2/20	0.35

▸	EPOR	P19235	2/20	0.34

▸	HTR2A	P28223	1/20	0.33

▸	CYP1A2	P05177	1/20	0.33

▸	TSHR	P16473	1/20	0.33

▸	DPP7	Q9UHL4	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12466708	0.88	KMT2A (0.49)	KMT2ATLR2CASP3FABP5FABP7
SCHEMBL27527132	0.88	CASP3 (0.38)	KMT2ATLR2CA1CA2CASP3
SCHEMBL29557381	0.80	KMT2A (0.44)	KMT2ATLR2CA1CA2CASP3
SCHEMBL28516143	0.80	KMT2A (0.44)	KMT2ATLR2CA1CA2CASP3
SCHEMBL569185	0.80	KMT2A (0.44)	KMT2ATLR2CA1CA2CASP3
SCHEMBL29413321	0.78	KMT2A (0.43)	KMT2ATLR2CA1CA2CASP3
SCHEMBL30140912	0.78	KMT2A (0.43)	KMT2ATLR2CASP3FABP5FABP7
SCHEMBL31714158	0.78	KMT2A (0.43)	KMT2ATLR2CASP3FABP5FABP7
SCHEMBL30350460	0.78	KMT2A (0.43)	KMT2ATLR2CASP3FABP5FABP7
SCHEMBL26009028	0.78	KMT2A (0.43)	KMT2ATLR2CASP3FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008089485-A2	CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION	THE CLEVELAND CLINIC FOUNDATION (US)	2008-07-24	—	—	WO	disclosed