Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FABP7 | O15540 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740141 | 0.88 | KMT2A (0.38) | KMT2ACASP3CYP1A2TSHRFABP7 | |
| SCHEMBL27527132 | 0.87 | CASP3 (0.38) | KMT2ACASP3FABP7FABP5TLR2 | |
| SCHEMBL29277349 | 0.78 | KMT2A (0.55) | KMT2ACASP3FABP7FABP5TLR2 | |
| SCHEMBL29277350 | 0.78 | KMT2A (0.55) | KMT2ACASP3FABP7FABP5TLR2 | |
| SCHEMBL27042592 | 0.77 | CASP3 (0.35) | KMT2ACASP3CYP1A2TSHRFABP7 | |
| SCHEMBL289035 | 0.77 | FABP5 (0.40) | KMT2ACASP3CYP1A2TSHRFABP7 | |
| SCHEMBL1557276 | 0.74 | PPARG (0.41) | KMT2ACASP3 | |
| SCHEMBL1556697 | 0.74 | OPRM1 (0.38) | KMT2ACASP3 | |
| SCHEMBL5972005 | 0.73 | KMT2A (0.70) | KMT2ACASP3FABP7FABP5EGFR | |
| SCHEMBL2401694 | 0.73 | KMT2A (0.70) | KMT2ACASP3FABP7FABP5EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103328-A1 | LABELED, NON- PEPTIDIC MULTIVALENT INTEGRIN ALPHA -V - BETA - 3 ANTAGONISTS, COMPOSITIONS CONTAINING THEM AND THEIR USE | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2012-08-02 | — | — | WO | disclosed |