Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856199 | 0.81 | CYP11B1 (0.51) | POLBKDM4ECYP11B1CYP11B2KMT2A | |
| SCHEMBL9031269 | 0.81 | ROCK2 (0.73) | POLBKDM4ECYP11B1CYP11B2KMT2A | |
| SCHEMBL29362556 | 0.81 | ROCK2 (0.73) | POLBKDM4ECYP11B1CYP11B2KMT2A | |
| SCHEMBL4784930 | 0.80 | MEN1 (0.52) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28901021 | 0.79 | NPC1 (0.67) | POLBGAAKMT2AMEN1MAPT | |
| SCHEMBL31006497 | 0.72 | GAA (0.61) | POLBKDM4ECYP11B1CYP11B2GAA | |
| SCHEMBL28871748 | 0.72 | GAA (0.61) | POLBKDM4ECYP11B1CYP11B2GAA | |
| SCHEMBL1686736 | 0.72 | ALDH1A1 (0.52) | KDM4EGAAALDH1A1THRBHTT | |
| SCHEMBL4737020 | 0.72 | MAOB (0.51) | POLBGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL28056929 | 0.71 | ATG4B (0.59) | KDM4EKMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |