Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31664562 | 0.82 | ALDH1A1 (1.00) | ALDH1A1GAASMN1; SMN2HTTKDM4E | |
| SCHEMBL31108064 | 0.79 | L3MBTL1 (0.46) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL20595429 | 0.79 | L3MBTL1 (0.46) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL4279550 | 0.79 | L3MBTL1 (0.54) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL27188742 | 0.78 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL1551850 | 0.77 | L3MBTL1 (0.55) | SMN1; SMN2HTTL3MBTL1STAT3KDM4E | |
| SCHEMBL30986715 | 0.77 | L3MBTL1 (0.55) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL28485531 | 0.77 | L3MBTL1 (0.64) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL31574614 | 0.77 | L3MBTL1 (0.55) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL5445494 | 0.76 | ALDH1A1 (0.69) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |