Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28485531 | 0.81 | L3MBTL1 (0.64) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL31574614 | 0.81 | L3MBTL1 (0.55) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL30986715 | 0.81 | L3MBTL1 (0.55) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL27493148 | 0.77 | TLR8 (0.55) | L3MBTL1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL27621425 | 0.77 | HTT (0.68) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL4740388 | 0.77 | ALDH1A1 (0.69) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL27906795 | 0.76 | HRH4 (0.47) | HTTSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL4740384 | 0.75 | L3MBTL1 (0.52) | L3MBTL1HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL12970296 | 0.74 | TLR8 (0.49) | SMN1; SMN2STAT3MAPTLMNAKDM4E | |
| SCHEMBL17164561 | 0.74 | L3MBTL1 (0.51) | L3MBTL1HTTSMN1; SMN2STAT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313394-A1 | NOVEL TETRAMETHYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2011-04-27 | — | — | EP | disclosed |
| WO-2009156396-A1 | NOVEL TETRAMETHYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-12-30 | — | — | WO | disclosed |