Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13427422 | 1.00 | CYP3A4 (0.49) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL16379575 | 1.00 | CYP3A4 (0.49) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL4739320 | 1.00 | CYP3A4 (0.49) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL6512353 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL6512348 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL9090998 | 0.87 | CYP2C19 (0.39) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL9091143 | 0.87 | CYP2C19 (0.39) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL9090855 | 0.86 | CYP3A4 (0.38) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL15982051 | 0.84 | CYP3A4 (0.46) | CYP3A4CYP2C19MAPTALDH1A1TSHR | |
| SCHEMBL12573467 | 0.84 | CYP3A4 (0.46) | CYP3A4CYP2C19MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158155-A1 | Cell Surface Receptor Binding Compounds and Conjugates | LYCIA THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20220135609-A1 | Mannose Derivatives for Treating Bacterial Infections | VERTEX PHARMA (US) | 2022-05-05 | — | — | US | disclosed |
| US-10913761-B2 | 2,7-dibromospiro[fluorene-9,4′-piperidine] compounds | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200270293-A1 | Mannose Derivatives for Treating Bacterial Infections | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2020-08-27 | — | — | US | disclosed |
| US-10669298-B2 | Mannose derivatives for treating bacterial infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-06-02 | — | — | US | disclosed |
| WO-2020035782-A1 | MOLECULAR PROBES FOR ANALYSIS OF METABOLISM OF GLYCOLYSIS INHIBITORS PRODRUGS AND SYNTHESIS METHODS THEREFORE | DERMIN SP. Z O.O. (PL) | 2020-02-20 | — | — | WO | disclosed |
| US-20190106450-A1 | Mannose Derivatives for Treating Bacterial Infections | VERTEX PHARMACEUTICALS INCORPORATED | 2019-04-11 | — | — | US | disclosed |
| EP-2935302-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2008081270-A2 | PROCESS FOR THE PREPARATION OF 3.6-DI-O-ACETYL-D-GLYCALS | INNOVATIVE BIOTECHNOLOGY S.R.L. (IT) | 2008-07-10 | — | — | WO | disclosed |
| US-5496930-A | Unsaturatd sugar compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0337920-B1 | Process for high regioselective esterification and ether-cleavage on unsaturated sugar compounds with the help of lipases and esterases and products obtained with that process | HOECHST AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| EP-0507278-A2 | Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-07 | — | — | EP | disclosed |
| EP-0337920-A2 | Process for high regioselective esterification and ether-cleavage on unsaturated sugar compounds with the help of lipases and esterases and products obtained with that process | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158155-A1 | Cell Surface Receptor Binding Compounds and Conjugates | M6PR, ASGR1, IGF2R | CYP3A4 3731/4885CYP2C19 4544/4885MAPT 3180/4885 |
| US-20190106450-A1 | Mannose Derivatives for Treating Bacterial Infections | MPI, MANBA, MAN2A1 | CYP3A4 3435/4885CYP2C19 2197/4885MAPT 3571/4885 |
| US-10913761-B2 | 2,7-dibromospiro[fluorene-9,4′-piperidine] compounds | DHPS, CFTR, FDPS | CYP3A4 838/4885CYP2C19 97/4885MAPT 4611/4885 |
| US-20220135609-A1 | Mannose Derivatives for Treating Bacterial Infections | MPI, MANBA, MAN2A1 | CYP3A4 3435/4885CYP2C19 2197/4885MAPT 3571/4885 |
| US-10669298-B2 | Mannose derivatives for treating bacterial infections | MPI, MANBA, MAN2A1 | CYP3A4 3435/4885CYP2C19 2197/4885MAPT 3571/4885 |
| US-20200270293-A1 | Mannose Derivatives for Treating Bacterial Infections | MPI, MANBA, MAN2A1 | CYP3A4 3435/4885CYP2C19 2197/4885MAPT 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.