Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979633 | 0.90 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL1198591 | 0.84 | MAPT (0.81) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL4462657 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL15655703 | 0.82 | TRPM8 (0.75) | ALDH1A1SMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL15656353 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL28836012 | 0.82 | KMT2A (0.74) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL29782929 | 0.82 | KMT2A (0.74) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL29071267 | 0.82 | KMT2A (0.74) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL30659931 | 0.82 | KMT2A (0.74) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| Lithium Ion SCHEMBL27657109 | 0.81 | MAPT (0.77) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |