Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 3/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | SI | P14410 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303567 | 0.87 | MAOA (0.79) | MAOAGAAACHEMGAMSI | |
| SCHEMBL4740846 | 0.87 | MAOA (0.79) | MAOAGAAACHEMGAMSI | |
| SCHEMBL4742596 | 0.86 | MAOA (0.71) | MAOAGAAACHEMGAMSI | |
| Decursinol Angelate SCHEMBL3901154 | 0.83 | MAOA (0.76) | MAOAGAAACHEMGAMSI | |
| Decursinol Angelate SCHEMBL4740622 | 0.83 | MAOA (0.76) | MAOAGAAACHEMGAMSI | |
| Decursinol Angelate SCHEMBL14310264 | 0.83 | MAOA (0.76) | MAOAGAAACHEMGAMSI | |
| Decursinol Angelate SCHEMBL3901157 | 0.83 | MAOA (0.76) | MAOAGAAACHEMGAMSI | |
| SCHEMBL14105695 | 0.83 | MAOA (0.73) | MAOAGAAACHEMGAMSI | |
| Decursin SCHEMBL14511556 | 0.82 | MAOA (1.00) | MAOAGAAACHEMGAMSI | |
| Decursin SCHEMBL3904733 | 0.82 | MAOA (1.00) | MAOAGAAACHEMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008102994-A1 | COMPOSITION COMPRISING DECURSIN DERIVATIVE FOR TREATING AND PREVENTING ATOPIC DERMATITIS | PARK YONG JIN (KR) | 2008-08-28 | — | — | WO | disclosed |