Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734260 | 0.81 | LTB4R2 (0.64) | LTB4R2KMT2AMEN1NR1H4 | |
| SCHEMBL6831433 | 0.80 | LTB4R2 (0.54) | LTB4R2KMT2AMEN1NR1H4 | |
| SCHEMBL4089396 | 0.80 | CHRM2 (0.52) | LTB4R2KMT2AMEN1L3MBTL1 | |
| SCHEMBL6827496 | 0.79 | RAB9A (0.53) | LTB4R2ACHEKMT2AMEN1L3MBTL1 | |
| SCHEMBL4681290 | 0.79 | RELA (0.45) | GAAKMT2AMEN1LMNAMAPT | |
| SCHEMBL6830534 | 0.78 | LTB4R2 (0.50) | LTB4R2KMT2AMEN1NR1H4L3MBTL1 | |
| SCHEMBL4677800 | 0.76 | LTB4R2 (0.50) | LTB4R2KMT2AMEN1L3MBTL1 | |
| SCHEMBL4079862 | 0.74 | CHRM2 (0.55) | LTB4R2ACHEKMT2AMEN1NR1H4 | |
| SCHEMBL24751456 | 0.73 | HDAC1 (0.45) | GAALTB4R2KMT2AMEN1NR1H4 | |
| SCHEMBL29938594 | 0.73 | HDAC1 (0.45) | GAALTB4R2KMT2AMEN1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |