Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827496 | 0.92 | RAB9A (0.53) | LTB4R2MEN1KMT2APTPRBRAB9A | |
| SCHEMBL4734260 | 0.91 | LTB4R2 (0.64) | LTB4R2MEN1KMT2APTPRBRAB9A | |
| SCHEMBL4089396 | 0.90 | CHRM2 (0.52) | LTB4R2MEN1KMT2APTPRBPTGDR2 | |
| SCHEMBL4677800 | 0.89 | LTB4R2 (0.50) | LTB4R2MEN1KMT2APTPRBPTGDR2 | |
| SCHEMBL6830534 | 0.88 | LTB4R2 (0.50) | LTB4R2MEN1KMT2APTPRBRAB9A | |
| SCHEMBL4237307 | 0.86 | ALDH1A1 (0.54) | LTB4R2MEN1KMT2AMAPK14RAB9A | |
| SCHEMBL4079862 | 0.86 | CHRM2 (0.55) | LTB4R2MEN1KMT2APTPRBRAB9A | |
| SCHEMBL4740647 | 0.80 | GAA (0.49) | LTB4R2MEN1KMT2ANR1H4 | |
| SCHEMBL4244213 | 0.80 | KDM4E (0.48) | LTB4R2PTPRBPTGDR2RAB9ACETP | |
| SCHEMBL28229571 | 0.80 | LTB4R2 (0.60) | LTB4R2MEN1KMT2APTPRBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461336-A2 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053966-A2 | 1-ALKYL-1-AZONIABICYCLO [2.2.2] OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2003-07-03 | — | — | WO | disclosed |