Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785798 | 1.00 | SLC6A9 (0.48) | SLC6A9SLC6A4HRH3HTR1ACYP2D6 | |
| SCHEMBL4738511 | 0.90 | SLC6A9 (0.50) | SLC6A9SLC6A4HRH3HTR1ACYP2D6 | |
| SCHEMBL4736090 | 0.90 | SLC6A9 (0.50) | SLC6A9SLC6A4HRH3HTR1ACYP2D6 | |
| SCHEMBL4740321 | 0.76 | SLC6A9 (0.57) | SLC6A9SLC6A4HRH3HTR1ACYP2D6 | |
| SCHEMBL7318201 | 0.75 | SLC6A9 (0.60) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| Oxalic Acid SCHEMBL4740319 | 0.69 | SLC6A4 (0.72) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| SCHEMBL13780465 | 0.68 | SLC6A9 (0.77) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| SCHEMBL7935252 | 0.68 | SLC6A4 (0.75) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| SCHEMBL4739538 | 0.68 | SLC6A9 (0.52) | SLC6A9SLC6A4HRH3HTR1ACYP2D6 | |
| SCHEMBL5287841 | 0.68 | CYP1A2 (0.43) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |