Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.75 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.61 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MTOR | P42345 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8723130 | 0.99 | SLC6A4 (0.73) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL4740934 | 0.88 | SLC6A9 (0.67) | SLC6A4HRH3SLC6A9CYP2D6CYP2C19 | |
| SCHEMBL10076387 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL7943264 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL8726521 | 0.88 | SLC6A9 (0.63) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL12186131 | 0.87 | SLC6A9 (0.70) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL29700710 | 0.86 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL679320 | 0.86 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL9398426 | 0.85 | SLC6A4 (0.75) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL15127607 | 0.84 | SLC6A9 (1.00) | SLC6A4HRH3SLC6A9CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010412-A2 | METHOD FOR THE PREPARATION OF N-METHYL-ARYLOXY-PROPANAMINE DERIVATIVES | LUKÁCS, Gyula (HU) | 2010-01-28 | — | — | WO | disclosed |
| EP-0929514-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS GYOGYSZERGYAR RT. (HU) | 1999-07-21 | — | — | EP | disclosed |
| EP-0617006-B1 | N-Substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and procedure for their preparation | PLIVA PHARM & CHEM WORKS (HR) | 1998-05-06 | — | — | EP | disclosed |
| WO-1998011054-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS Gyógyszergyár Rt. (HU) | 1998-03-19 | — | — | WO | disclosed |
| US-5618968-A | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA FARMACEUTSKA KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1997-04-08 | — | — | US | disclosed |
| EP-0617006-A1 | N-subtituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA d.d. ZAGREB (HR) | 1994-09-28 | — | — | EP | disclosed |