Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 15/20 | 0.43 |
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146343 | 0.93 | KDM4E (0.44) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4739636 | 0.87 | PPARA (0.55) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4739620 | 0.84 | PPARA (0.46) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4741580 | 0.82 | PPARA (0.56) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL217852 | 0.82 | KEAP1 (0.39) | PPARDPPARAPPARG | |
| SCHEMBL14146847 | 0.81 | PPARA (0.45) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4739616 | 0.80 | ALDH1A1 (0.55) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4740521 | 0.79 | PPARA (0.45) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL14146447 | 0.79 | PPARA (0.42) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4737303 | 0.77 | PPARA (0.48) | NPC1ALDH1A1GAAPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |