Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743152 | 0.91 | HPGD (0.58) | MAPTHPGDRAB9AESRRASMN1; SMN2 | |
| SCHEMBL4787074 | 0.81 | HPGD (0.73) | MAPTHPGDRAB9AESRRASCN7A | |
| SCHEMBL4377200 | 0.79 | KMT2A (0.39) | MAPTHPGDALDH1A1GLAGAA | |
| SCHEMBL9619696 | 0.78 | HPGD (0.79) | MAPTHPGDRAB9AESRRASCN7A | |
| SCHEMBL19446390 | 0.73 | HPGD (0.56) | MAPTHPGDRAB9AESRRASMN1; SMN2 | |
| SCHEMBL9619566 | 0.72 | MAPT (0.68) | MAPTHPGDRAB9AESRRASCN7A | |
| SCHEMBL9619563 | 0.70 | RAB9A (0.66) | MAPTHPGDRAB9AESRRASCN7A | |
| SCHEMBL3301210 | 0.69 | HPGD (1.00) | MAPTHPGDRAB9AESRRASMN1; SMN2 | |
| SCHEMBL203697 | 0.69 | HPGD (1.00) | MAPTHPGDRAB9AESRRASMN1; SMN2 | |
| SCHEMBL3719405 | 0.68 | MAPT (0.60) | MAPTHPGDRAB9AESRRACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099415-A1 | NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |