Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 17/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935252 | 0.88 | SLC6A4 (0.75) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8723130 | 0.87 | SLC6A4 (0.73) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4783308 | 0.85 | MEN1 (0.54) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4736867 | 0.83 | SLC6A9 (0.51) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL7317614 | 0.82 | SLC6A4 (0.88) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| SCHEMBL13780465 | 0.82 | SLC6A9 (0.77) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| SCHEMBL1171367 | 0.81 | SLC6A9 (1.00) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| SCHEMBL15127607 | 0.81 | SLC6A9 (1.00) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| SCHEMBL6259757 | 0.79 | SLC6A9 (0.80) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| SCHEMBL8726521 | 0.79 | SLC6A9 (0.63) | SLC6A9SLC6A4HRH3CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |