Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 12/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4740934 | 0.83 | SLC6A9 (0.67) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4739725 | 0.81 | HTR1A (0.67) | SLC6A9HTR1ASLC6A4HRH3 | |
| Oxalic Acid SCHEMBL4739539 | 0.80 | HTR1A (0.66) | SLC6A9HTR1ASLC6A4HRH3 | |
| SCHEMBL7935252 | 0.75 | SLC6A4 (0.75) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4784368 | 0.74 | HTR1A (0.61) | SLC6A9HTR1ASLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL8723130 | 0.74 | SLC6A4 (0.73) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4783308 | 0.74 | MEN1 (0.54) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4740319 | 0.73 | SLC6A4 (0.72) | SLC6A9SLC6A4HRH3ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL4785219 | 0.73 | HTR1A (0.67) | SLC6A9HTR1ASLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7437107 | 0.72 | SLC6A4 (0.56) | SLC6A9HTR1ASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |