Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338109 | 0.86 | MEN1 (0.48) | GBA1RAB9AHTR6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL26911935 | 0.82 | HTR6 (0.52) | GBA1RAB9AHTR6ALDH1A1SLC9A1 | |
| Hydrochloric Acid SCHEMBL30611197 | 0.82 | HTR6 (0.52) | GBA1RAB9AHTR6ALDH1A1SLC9A1 | |
| SCHEMBL1544929 | 0.80 | HTR6 (0.56) | HTR6 | |
| SCHEMBL1545834 | 0.79 | ALOX15 (0.46) | HTR6GAAALDH1A1KMT2ASMO | |
| SCHEMBL8789689 | 0.75 | HTR6 (0.63) | HTR6 | |
| SCHEMBL1545076 | 0.74 | HTR6 (0.43) | GBA1HTR6GAAPKMALDH1A1 | |
| SCHEMBL12253486 | 0.74 | SLC9A1 (0.56) | HTR6GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL12253466 | 0.72 | NR1H2 (0.56) | HTR6GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL9400073 | 0.72 | ELANE (0.52) | GBA1ALOX5GAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984351-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007098418-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-08-30 | — | — | WO | disclosed |