SCHEMBL474098

SCHEMBL474098

O=Cc1c[nH]c(-c2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.41
MTOR P42345 1/20 0.38
ADK P55263 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
DCUN1D1 Q96GG9 2/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
TNKS O95271 1/20 0.37
PARP1 P09874 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 3/20 0.36
CYP2C19 P33261 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8327153 0.83 GRIA1 (0.37) MEN1KMT2AALDH1A1CYP1A2KDM4E
SCHEMBL2555001 0.81 KDM4E (0.41) DCUN1D1NR1H2NR1H3TNKSTNKS2
SCHEMBL15332789 0.81 KDM4E (0.38) TNKSPARP1TNKS2ALDH1A1NPC1
SCHEMBL15331942 0.81 ALDH1A1 (0.41) TNKSPARP1TNKS2MEN1KMT2A
SCHEMBL8963381 0.81 NISCH (0.42) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL15331294 0.81 MAP2K1 (0.33)
SCHEMBL15330777 0.81 TNKS2 (0.37) NR1H2NR1H3TNKSPARP1TNKS2
SCHEMBL15332054 0.81 PIN1 (0.44) NISCHMEN1KMT2AKDM4EGAA
SCHEMBL29957264 0.81 CYP11B1 (0.41) NISCHALDH1A1CYP1A2NPC1RAB9A
SCHEMBL29951043 0.81 BTK (0.49) BTKKMT2AALDH1A1CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204696-A1 PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF DESIGNER MOLECULES, INC 2022-06-30 US claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
CN-108291122-B Anionically curable compositions 设计分子有限公司 2021-01-05 CN claimed
WO-2020219852-A1 PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF DESIGNER MOLECULES, INC. (US) 2020-10-29 WO claimed
US-20180237668-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. 2018-08-23 US claimed
EP-3331959-A1 ANIONIC CURABLE COMPOSITIONS Designer Molecules, Inc. (US) 2018-06-13 EP claimed
WO-2017027482-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2017-02-16 WO claimed
JP-2005530823-A 2005-10-13 JP claimed
US-20050215553-A1 Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation AVENTIS PHARMA S.A. (FR) 2005-09-29 US claimed
EP-1515953-A2 NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME Aventis Pharma S.A. (FR) 2005-03-23 EP claimed
WO-2003106431-A2 NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME AVENTIS PHARMA S.A. (FR) 2003-12-24 WO claimed
CN-119548495-A Use of (substituted 1H-imidazol-4-yl) (3, 4, 5-trimethoxyphenyl) methanones for the treatment of coronaviruses 维鲁公司 2025-03-04 CN disclosed
CN-119432072-A Resin composition 味之素株式会社 2025-02-14 CN disclosed
EP-4504183-A1 METHODS OF TREATING INFLUENZA AND POXVIRUS VIRAL INFECTIONS Veru Inc. (US) 2025-02-12 EP disclosed
CN-117396505-A Methods of treating inflammation 维鲁公司 2024-01-12 CN disclosed
US-RE30511-E ENZYME INHIBITOR, HERBICIDE, CYCLIZATION AMERICAN CYANAMID COMPANY (US) 1981-02-10 US disclosed
US-4168964-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1979-09-25 US disclosed
US-4126444-A Substituted imidazo (1,5-D)-as-triazin-4-ols, and herbicidal use thereof AMERICAN CYNAMID COMPANY (US) 1978-11-21 US disclosed
US-4124766-A INTERMEDIATES FOR PHOSPHODIESTERASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-11-07 US disclosed
US-4107307-A ENZYME INHIBITORS, HERBICIDES, RING CLOSURE AMERICAN CYANAMID COMPANY (US) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215553-A1 Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation HK1, ACE, CTSZ BTK 1221/4885MTOR 580/4885ADK 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.