Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 8/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MYOC | Q99972 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953332 | 0.88 | MEN1 (0.75) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL4740981 | 0.86 | MEN1 (0.54) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL29251385 | 0.82 | MEN1 (0.53) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL28880742 | 0.81 | PNLIP (0.52) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL5170350 | 0.81 | MEN1 (0.48) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL1532248 | 0.80 | KMT2A (0.59) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL22065253 | 0.79 | MEN1 (0.46) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL29130767 | 0.78 | MAPT (0.58) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL7125255 | 0.77 | RORC (0.62) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL810717 | 0.77 | ALDH3A1 (0.51) | KMT2AMEN1GAAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |