Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679959 | 0.89 | RAB9A (0.81) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL15656938 | 0.88 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTALDH1A1ALOX5 | |
| SCHEMBL3419091 | 0.88 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTALDH1A1ALOX5 | |
| SCHEMBL290403 | 0.87 | APP (0.55) | RAB9ASMN1; SMN2MAPTALDH1A1ALOX5 | |
| SCHEMBL3068544 | 0.86 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2MAPTALDH1A1ALOX5 | |
| SCHEMBL10996350 | 0.86 | LMNA (0.58) | RAB9ASMN1; SMN2MAPTALDH1A1ALOX5 | |
| SCHEMBL27589477 | 0.85 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28836113 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL15656858 | 0.84 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL15654609 | 0.83 | RAB9A (0.72) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |