Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742099 | 0.88 | LMNA (0.55) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4743456 | 0.85 | MAPT (0.47) | MAPTCKS1BSKP1SKP2PTPN11 | |
| SCHEMBL4743444 | 0.84 | USP2 (0.54) | LMNAMAPTCKS1BSKP1SKP2 | |
| SCHEMBL31220479 | 0.84 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1METCKS1B | |
| SCHEMBL2977592 | 0.81 | ALDH1A1 (0.63) | LMNAMAPTALDH1A1METCKS1B | |
| SCHEMBL4743406 | 0.80 | MET (0.39) | LMNAMAPTALDH1A1METCKS1B | |
| SCHEMBL4742143 | 0.80 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1METCKS1B | |
| SCHEMBL4786909 | 0.80 | MET (0.39) | LMNAMAPTALDH1A1METPTPN11 | |
| SCHEMBL28520810 | 0.78 | MTOR (0.64) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2973720 | 0.76 | ALDH1A1 (0.73) | LMNAMAPTALDH1A1METSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |