SCHEMBL4742281

SCHEMBL4742281

CC(C)(C)Oc1ccc2c(c1C(=O)O)Cc1ccccc1O2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
ACSL1 P33121 1/20 0.38
GSR P00390 1/20 0.32
MAPKAPK2 P49137 1/20 0.32
KCNH2 Q12809 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
PMP22 Q01453 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742293 0.85 ALOX5 (0.55) ALOX5MAOAMAOBACSL1MEN1
SCHEMBL4745471 0.82 CXCR5 (0.42) ALOX5MAOAMAOBACSL1MEN1
SCHEMBL4742918 0.79 CA9 (0.39) ALOX5MAOAMAOBACSL1ALDH1A1
SCHEMBL4742913 0.78 ALOX5 (0.38) ALOX5MAOAMAOBACSL1
SCHEMBL1672256 0.78 MAOA (0.47) ALOX5MAOAMAOBACSL1GSR
SCHEMBL4298022 0.78 MAOA (0.47) ALOX5MAOAMAOBACSL1GSR
SCHEMBL4747022 0.77 PTPN11 (0.43) MEN1ALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4746926 0.77 PTPN11 (0.43) MEN1ALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4745086 0.77 PTPN11 (0.43) MEN1ALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4743732 0.77 PTPN11 (0.43) MEN1ALDH1A1CYP3A4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008113814-A1 ORGANIC MOLYBDENUM COMPOUNDS, USE THEREOF AS FRICTION- MODIFIERS AND LUBRICATING COMPOSITIONS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-09-25 WO disclosed