Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743201 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL4742790 | 0.69 | KMT2A (0.54) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL14102180 | 0.69 | KMT2A (0.75) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL4740862 | 0.67 | ALDH1A1 (0.58) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL14102109 | 0.67 | KMT2A (0.63) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL31358249 | 0.67 | ALDH1A1 (0.61) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL12821043 | 0.67 | ALDH1A1 (0.61) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL13704047 | 0.66 | ALDH1A1 (0.71) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL13704104 | 0.66 | KDM4E (0.59) | MEN1KMT2AHPGDPKMALDH1A1 | |
| SCHEMBL31358570 | 0.65 | ALDH1A1 (0.61) | MEN1KMT2AHPGDPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |