Quinquangulin

Quinquangulin

SCHEMBL4742445

COc1cc(O)c2c(O)c3c(=O)cc(C)oc3cc2c1C

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 9/20 0.64
PTGS2 P35354 9/20 0.64
XDH P47989 1/20 0.58
HIF1A Q16665 2/20 0.53
EPAS1 Q99814 2/20 0.53
KDM4E B2RXH2 3/20 0.51
MAPT P10636 3/20 0.51
TP53 P04637 2/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
ALOX15 P16050 1/20 0.51
RECQL P46063 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ABCB1 P08183 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
CYP3A4 P08684 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8860537 0.90 PTGS1 (0.64) PTGS1PTGS2XDHHIF1AEPAS1
SCHEMBL8860175 0.86 XDH (0.61) PTGS1PTGS2XDHHIF1AEPAS1
SCHEMBL29403680 0.83 PTGS1 (0.80) PTGS1PTGS2XDHHIF1AEPAS1
SCHEMBL16226550 0.80 XDH (0.70) PTGS1PTGS2XDHHIF1AEPAS1
SCHEMBL8860230 0.80 XDH (0.67) PTGS1PTGS2XDHHIF1AEPAS1
Ustilaginoidin A SCHEMBL3119631 0.79 PTGS1 (0.62) PTGS1PTGS2XDHHIF1AEPAS1
SCHEMBL30105701 0.77 CYP3A4 (0.69) PTGS1PTGS2XDHHIF1AEPAS1
Stellatin SCHEMBL29368317 0.76 PTGS1 (1.00) PTGS1PTGS2XDHKDM4EMAPT
SCHEMBL8860458 0.76 PTGS1 (0.48) PTGS1PTGS2XDHHIF1AEPAS1
Rubrofusarin SCHEMBL486101 0.75 XDH (0.79) PTGS1PTGS2XDHHIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
US-20170298209-A1 USE OF A QUINONE COMPOUND IN BUILDING MATERIALS ARKION LIFE SCIENCES, LLC (US) 2017-10-19 US disclosed
US-20150208657-A1 USE OF QUINONE COMPOUND IN BUILDING MATERIALS ARKION LIFE SCIENCES, LLC (US) 2015-07-30 US disclosed
US-20140335050-A1 METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER THE GENERAL HOSPITAL CORPORATION (US) 2014-11-13 US disclosed
WO-2012136782-A1 METHOD OF DYEING OR MAKING UP KERATIN FIBRES USING A PIGMENT RESULTING FROM A 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE, COMPOSITION CONTAINING THE PIGMENT AND THE PIGMENT L'OREAL (FR) 2012-10-11 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140335050-A1 METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER IL2RA, CD74, IL2 PTGS1 1807/4885PTGS2 1948/4885XDH 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.