Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860537 | 0.83 | PTGS1 (0.64) | PTGS1PTGS2XDHKDM4ELMNA | |
| SCHEMBL8860175 | 0.80 | XDH (0.61) | PTGS1PTGS2XDHKDM4ELMNA | |
| Ustilaginoidin A SCHEMBL3119631 | 0.79 | PTGS1 (0.62) | PTGS1PTGS2XDHKDM4ELMNA | |
| Quinquangulin SCHEMBL4742445 | 0.76 | PTGS1 (0.64) | PTGS1PTGS2XDHKDM4ELMNA | |
| SCHEMBL8860230 | 0.74 | XDH (0.67) | PTGS1PTGS2XDHKDM4ELMNA | |
| Rubrofusarin SCHEMBL486101 | 0.67 | XDH (0.79) | PTGS1PTGS2XDHKDM4ELMNA | |
| SCHEMBL8860220 | 0.67 | PTGS1 (0.46) | PTGS1PTGS2XDHKDM4ELMNA | |
| SCHEMBL1673012 | 0.66 | PTGS1 (0.62) | PTGS1PTGS2XDHKDM4ELMNA | |
| Eugenitol SCHEMBL29881346 | 0.66 | PTGS1 (0.77) | PTGS1PTGS2XDHKDM4ELMNA | |
| SCHEMBL8860206 | 0.65 | XDH (0.46) | PTGS1PTGS2XDHKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614642-A | Methods of inhibiting phosphatase activity and treatment of disorders associated therewith using naphthopyrones and derivatives thereof | SUGEN INC. (US) | 1997-03-25 | — | — | US | disclosed |
| US-5602171-A | Methods of inhibiting phosphatase activity and treatment of disorders associated therewith using naphthopyrones and derivatives thereof | SUGEN INC. (US) | 1997-02-11 | — | — | US | disclosed |