Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360174 | 0.82 | HRH3 (0.42) | HRH3SMN1; SMN2HRH4ACHEHTR2A | |
| SCHEMBL24204800 | 0.79 | NCF1 (0.43) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL12772840 | 0.79 | NCF1 (0.39) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL24204675 | 0.78 | NCF1 (0.42) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL26042815 | 0.77 | L3MBTL1 (0.40) | L3MBTL1L3MBTL3HRH3ACHEALDH1A1 | |
| SCHEMBL24204398 | 0.76 | NCF1 (0.41) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL24352364 | 0.76 | CHRM5 (0.45) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL24319406 | 0.76 | ALDH1A1 (0.37) | L3MBTL1L3MBTL3ACHEALDH1A1NCF1 | |
| SCHEMBL354055 | 0.76 | TP53 (0.48) | SMN1; SMN2GAAALDH1A1TP53HBB | |
| SCHEMBL3211746 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409479-B1 | 1-GLYCINYL-4-(1-METHYLPIPERIDIN-4-YL)PIPERAZINES AND -PIPERIDINES AS FACTOR XA ANTAGONISTS | LILLY CO ELI (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1409479-A2 | 1-GLYCINYL-4-(1-METHYLPIPERIDIN-4-YL)PIPERAZINES AND -PIPERIDINES AS FACTOR XA ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |