Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742620 | 0.89 | THRB (0.64) | THRBMEN1KMT2AMAPK10MAPT | |
| SCHEMBL4739993 | 0.88 | THRB (0.54) | THRBHPGDSMN1; SMN2MAPTPDGFRB | |
| SCHEMBL4742104 | 0.84 | MAPT (0.53) | THRBMEN1KMT2ASMN1; SMN2MAPK10 | |
| SCHEMBL4742585 | 0.84 | THRB (0.75) | THRBMEN1KMT2AMAPK10MAPT | |
| SCHEMBL4743046 | 0.84 | THRB (0.78) | THRBMEN1KMT2ASMN1; SMN2MAPK10 | |
| SCHEMBL22396176 | 0.84 | MAPT (0.59) | THRBMEN1KMT2AMAPK10MAPT | |
| SCHEMBL2943134 | 0.83 | PDGFRB (0.63) | THRBMEN1KMT2ASMN1; SMN2MAPK10 | |
| SCHEMBL25656123 | 0.82 | MEN1 (0.55) | THRBMEN1KMT2AMAPK10MAPT | |
| SCHEMBL4785451 | 0.81 | MAPK1 (0.72) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23726472 | 0.80 | PDGFRB (0.59) | THRBMEN1KMT2ASMN1; SMN2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |