Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741642 | 0.90 | MAPT (0.64) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4743444 | 0.88 | USP2 (0.54) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4742099 | 0.86 | LMNA (0.55) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4742591 | 0.81 | THRB (0.72) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4742620 | 0.79 | THRB (0.64) | LMNAMAPTHTTKDM4ENPSR1 | |
| SCHEMBL22396176 | 0.79 | MAPT (0.59) | TP53LMNAMAPTNPSR1MEN1 | |
| SCHEMBL13262174 | 0.79 | MEN1 (0.48) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4742621 | 0.78 | USP2 (0.45) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL4742558 | 0.77 | USP2 (0.44) | MAPK1USP2TP53RECQLHSD17B10 | |
| SCHEMBL16637247 | 0.77 | USP2 (0.49) | MAPK1USP2TP53RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |