Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660516 | 0.82 | NR1H4 (0.41) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL10431913 | 0.81 | ESRRG (0.42) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL1783392 | 0.79 | LMNA (0.43) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL1783394 | 0.79 | LMNA (0.43) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL4797466 | 0.78 | NR1H4 (0.39) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL140663 | 0.77 | CES1 (0.44) | TP53TSHRALDH1A1 | |
| SCHEMBL3132115 | 0.77 | LMNA (0.42) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL3132110 | 0.77 | LMNA (0.42) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL5186509 | 0.75 | SMN1; SMN2 (0.43) | TP53TSHRNR1H4EPHX2LMNA | |
| SCHEMBL5494077 | 0.75 | SMN1; SMN2 (0.43) | TP53TSHRNR1H4EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096075-A2 | METHOD FOR THE ASYMMETRIC HYDROGENATION OF ENAMINE AND DEVICE FOR REALISING SAID METHOD | HOLIS TECHNOLOGIES (FR) | 2008-08-14 | — | — | WO | disclosed |