SCHEMBL474272

SCHEMBL474272

OCC(O)C(O)CCC(O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 2/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15404584 0.81 LMNA (0.40) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL10564366 0.79 LMNA (0.41) LMNAL3MBTL1TDP1KDM4E
E968 SCHEMBL13727065 0.78 LMNA (0.67) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL21014667 0.78 THRB (0.53) LMNAL3MBTL1TDP1THRBALDH1A1
E968 SCHEMBL36228 0.78
E968 SCHEMBL17766 0.78
E968 SCHEMBL6729753 0.78
E968 SCHEMBL2723809 0.78 LMNA (0.67) LMNAL3MBTL1TDP1THRBALDH1A1
E968 SCHEMBL10427336 0.78
E968 SCHEMBL17062 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220126258-A1 COMPOSITIONS AND FORMULATIONS FOR ENTRAPPING PROTEIN ON A SURFACE PURE TRANSPLANT SOLUTIONS L L C (US) 2022-04-28 US disclosed
US-11260363-B2 Compositions and methods for entrapping protein on a surface PURE TRANSPLANT SOLUTIONS L.L.C. (US) 2022-03-01 US disclosed
US-20200147580-A1 COMPOSITIONS AND METHODS FOR ENTRAPPING PROTEIN ON A SURFACE PURE TRANSPLANT SOLUTIONS L.L.C. 2020-05-14 US disclosed
US-10556218-B2 Compositions and methods for entrapping protein on a surface PURE TRANSPLANT SOLUTIONS L.L.C. (US) 2020-02-11 US disclosed
US-20190039041-A1 COMPOSITIONS AND METHODS FOR ENTRAPPING PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2019-02-07 US disclosed
EP-2997037-B1 USE OF A COMPOSITION FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA INC (US) 2018-11-21 EP disclosed
US-10105674-B2 Compositions and methods for entrapping protein on a surface GENOMICS USA, INC. (US) 2018-10-23 US disclosed
US-20170327599-A1 COMPOSITIONS AND METHODS FOR ENTRAPPING PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2017-11-16 US disclosed
US-9751069-B2 Compositions and methods for entrapping protein on a surface GENOMICS USA, INC. (US) 2017-09-05 US disclosed
WO-2014185960-A9 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2015-03-05 WO disclosed
US-20140342947-A1 Compositions and methods for entrapping protein on a surface GENOMICS USA INC 2014-11-20 US disclosed
US-8426162-B2 Process and apparatus for the microbial production of a specific product and methane AGRAFERM TECHNOLOGIES AG (DE) 2013-04-23 US disclosed
EP-2411032-A2 PLANT EXTRACTS FOR TREATING SKIN DISEASES Evoria GmbH (DE) 2012-02-01 EP disclosed
US-20100285548-A1 Process And Apparatus For The Microbial Production Of A Specific Product And Methane AGRAFERM TECHNOLOGIES AG (DE) 2010-11-11 US disclosed
WO-2010108488-A2 PLANT EXTRACTS FOR TREATING SKIN DISEASES EVORIA GMBH (DE) 2010-09-30 WO disclosed
EP-0162239-A1 Percutaneous absorption accelerator and preparation containing same Kao Corporation (JP) 1985-11-27 EP disclosed