SCHEMBL4742727

SCHEMBL4742727

COc1ccccc1NC(=O)C(N=Nc1c(C#N)cnn1-c1ncccn1)C1=Nc2ccccc2S(=O)(=O)N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
PSMD14 O00487 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
KDM4E B2RXH2 4/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
PDE9A O76083 1/20 0.33
GFER P55789 1/20 0.32
PIM1 P11309 1/20 0.32
LIMK1 P53667 1/20 0.32
USP2 O75604 3/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10280955 0.90
SCHEMBL4742659 0.83 KDM4E (0.38) MEN1KMT2AKDM4EIRAK4PDE9A
SCHEMBL4780174 0.82 GFER (0.41) MEN1PSMD14PKMKMT2ARXFP1
SCHEMBL4780194 0.80 GFER (0.40) MEN1PSMD14PKMKMT2ARXFP1
SCHEMBL4742957 0.80 GFER (0.40) MEN1KMT2AKDM4EIRAK4PDE9A
SCHEMBL4742667 0.79 MPO (0.38) MEN1PKMKMT2AKDM4EIRAK4
SCHEMBL4742662 0.79 PDE9A (0.38) MEN1PSMD14PKMKMT2ARXFP1
SCHEMBL4742664 0.78 PKM (0.39) MEN1PKMKMT2AKDM4EIRAK4
SCHEMBL4742670 0.78 LMNA (0.38) MEN1PSMD14PKMKMT2ARXFP1
SCHEMBL4743026 0.78 GFER (0.38) MEN1PSMD14PKMKMT2ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed