SCHEMBL4742819

SCHEMBL4742819

COc1ccc([C@H]2Oc3c(c(O)cc(O)c3[C@H]3C(=O)c4c(O)cc(O)cc4O[C@@H]3c3ccc(O)cc3)C(=O)[C@@H]2O)cc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLK1 P06870 1/20 0.58
KLK3 P07288 1/20 0.58
KLK2 P20151 1/20 0.58
KLK7 P49862 1/20 0.58
KLK6 Q92876 1/20 0.58
KLK5 Q9Y337 1/20 0.58
SLCO1B3 Q9NPD5 4/20 0.55
SLCO1B1 Q9Y6L6 4/20 0.55
SLCO2B1 O94956 3/20 0.55
CBS P35520 2/20 0.55
CYP3A4 P08684 4/20 0.55
ALOX15 P16050 4/20 0.55
MAPT P10636 3/20 0.55
HSD17B10 Q99714 3/20 0.55
RECQL P46063 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 2/20 0.55
ALOX12 P18054 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392355 1.00 KLK1 (0.58) KLK1KLK3KLK2KLK7KLK6
SCHEMBL17915837 1.00 KLK1 (0.58) KLK1KLK3KLK2KLK7KLK6
SCHEMBL6363033 0.90 KLK1 (0.66) KLK1KLK3KLK2KLK7KLK6
SCHEMBL28770111 0.90 KLK1 (0.66) KLK1KLK3KLK2KLK7KLK6
SCHEMBL6360019 0.90 KLK1 (0.66) KLK1KLK3KLK2KLK7KLK6
SCHEMBL29414343 0.89 KLK1 (0.72) KLK1KLK3KLK2KLK7KLK6
SCHEMBL6360284 0.89 KLK1 (0.72) KLK1KLK3KLK2KLK7KLK6
SCHEMBL16263265 0.89 KLK1 (0.72) KLK1KLK3KLK2KLK7KLK6
SCHEMBL29441285 0.87 SOST (0.67) KLK1KLK3KLK2KLK7KLK6
SCHEMBL16263267 0.86 RECQL (0.75) KLK1KLK3KLK2KLK7KLK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 US claimed
EP-2735312-B1 ANTI-GLYCATION AGENT COMPRISING A GARCINIA KOLA EXTRACT OR FRACTION UNIV ANGERS (FR) 2021-07-07 EP claimed
EP-2858641-B1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORP (US) 2017-09-06 EP claimed
US-9107849-B2 Anti-glycation agent comprising a Garcinia kola extract or fraction UNIVERSITE D'ANGERS (FR) 2015-08-18 US claimed
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2015-05-21 US claimed
EP-2858641-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF Corporation (US) 2015-04-15 EP claimed
EP-2735312-A1 ANTI-GLYCATION AGENT COMPRISING A GARCINIA KOLA EXTRACT OR FRACTION UNIVERSITE D'ANGERS (FR) 2014-05-28 EP claimed
US-20140142171-A1 ANTI-GLYCATION AGENT COMPRISING A GARCINIA KOLA EXTRACT OR FRACTION LABORATOIRE SHIGETA (FR) 2014-05-22 US claimed
WO-2013184884-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORPORATION (US) 2013-12-12 WO claimed
CN-117531228-A Use of coconut water as extraction solvent 巴斯夫美容护理法国公司 2024-02-09 CN disclosed
CN-110167527-B Use of coconut water as extraction solvent 巴斯夫美容护理法国公司 2023-11-17 CN disclosed
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 US disclosed
EP-2735312-B1 ANTI-GLYCATION AGENT COMPRISING A GARCINIA KOLA EXTRACT OR FRACTION UNIV ANGERS (FR) 2021-07-07 EP disclosed
EP-3562472-B1 USE OF COCONUT WATER AS EXTRACTION SOLVENT BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2021-05-19 EP disclosed
WO-2013184884-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORPORATION (US) 2013-12-12 WO disclosed
CN-101448395-A Compositions and methods for increasing the value of plant products, enhancing their commercial quality, enhancing their resistance to external agents and increasing their polyphenol content ANTONI LESCHOT SANHUEZA ANDRES (CL) 2009-06-03 CN disclosed
EP-2003968-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF Leschot Sanhueza, Andres Antonio (CL) 2008-12-24 EP disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US disclosed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234918-B2 Methods for botanical and/or algae extraction ALG1, ALG8, CUTA KLK1 953/4885KLK3 1265/4885KLK2 1123/4885
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 KLK1 2941/4885KLK3 4014/4885KLK2 3010/4885
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION ALG1, ALG8, CUTA KLK1 953/4885KLK3 1265/4885KLK2 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.