Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 1/20 | 0.72 |
| ▸ | KLK3 | P07288 | 1/20 | 0.72 |
| ▸ | KLK2 | P20151 | 1/20 | 0.72 |
| ▸ | KLK7 | P49862 | 1/20 | 0.72 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.72 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414343 | 1.00 | KLK1 (0.72) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL16263265 | 1.00 | KLK1 (0.72) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL16263267 | 0.97 | RECQL (0.75) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL4742855 | 0.97 | RECQL (0.75) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL6363033 | 0.95 | KLK1 (0.66) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL28770111 | 0.95 | KLK1 (0.66) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL6360019 | 0.95 | KLK1 (0.66) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL29441285 | 0.92 | SOST (0.67) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL4742819 | 0.89 | KLK1 (0.58) | KLK1KLK3KLK2KLK7KLK6 | |
| SCHEMBL30392355 | 0.89 | KLK1 (0.58) | KLK1KLK3KLK2KLK7KLK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245600-A1 | Novel antimalarial agent | OSAKA BIOSCIENCE INSTITUTE (JP) | 2005-11-03 | — | — | US | claimed |
| US-20050245600-A1 | Novel antimalarial agent | OSAKA BIOSCIENCE INSTITUTE (JP) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245600-A1 | Novel antimalarial agent | ARG2, GLS2, HAMP | KLK1 4826/4885KLK3 4820/4885KLK2 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.