Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | APOB | P04114 | 9/20 | 0.43 |
| ▸ | MTTP | P55157 | 8/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644649 | 0.77 | NAMPT (0.42) | SMOPTGESNAMPTLMNAPOLB | |
| SCHEMBL6644330 | 0.76 | SMO (0.49) | SMOAPOBMTTPLMNA | |
| SCHEMBL6648505 | 0.72 | LMNA (0.48) | SMOAPOBMTTPLMNAPOLB | |
| SCHEMBL6649355 | 0.71 | NAMPT (0.41) | NAMPT | |
| SCHEMBL6644922 | 0.71 | RAB9A (0.43) | NAMPTPOLB | |
| SCHEMBL6971759 | 0.69 | SMO (0.56) | SMOAPOBMTTPNAMPTLMNA | |
| SCHEMBL6646034 | 0.68 | APOB (0.48) | SMOAPOBMTTPNAMPTLMNA | |
| SCHEMBL6648330 | 0.68 | SCN10A (0.42) | NAMPTLMNAPOLB | |
| SCHEMBL6646925 | 0.68 | GFER (0.40) | NAMPTLMNA | |
| SCHEMBL6966884 | 0.68 | APOB (0.61) | SMOAPOBMTTPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090198-A1 | USE OF MTP INHIBITORS FOR INCREASING LEVELS OF SATIETY HORMONES | JANSSEN PHARMACEUTICA NV (BE) | 2008-07-31 | — | — | WO | claimed |
| WO-2008090198-A1 | USE OF MTP INHIBITORS FOR INCREASING LEVELS OF SATIETY HORMONES | JANSSEN PHARMACEUTICA NV (BE) | 2008-07-31 | — | — | WO | disclosed |