SCHEMBL4742873

SCHEMBL4742873

CC(=CCc1c(OC2OC(CO)C(O)C(O)C2O)cc(O)c2c1OC(c1ccc(O)cc1)C(O)C2=O)CCC(C)=CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c2c1O[C@H](c1ccc(O)cc1)[C@@H](O)C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 2/20 0.46
▸ SLCO2B1 O94956 2/20 0.46
▸ SLC28A3 Q9HAS3 4/20 0.43
▸ ABCG2 Q9UNQ0 1/20 0.42
▸ ACHE P22303 2/20 0.42
▸ SLC5A1 P13866 3/20 0.42
▸ KDM1A O60341 2/20 0.42
▸ SYNJ2 O15056 1/20 0.41
▸ HPGD P15428 2/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ ESR1 P03372 1/20 0.41
▸ ESR2 Q92731 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ SLC5A2 P31639 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phellamurin SCHEMBL27013577 0.94 PTPN1 (0.47) PTPN1SLCO2B1SLC28A3ABCG2SLC5A1
Phellamurin SCHEMBL30291874 0.94 PTPN1 (0.47) PTPN1SLCO2B1SLC28A3ABCG2SLC5A1
SCHEMBL19463534 0.81 PTPN1 (0.62) PTPN1SLCO2B1ABCG2ACHEKDM1A
SCHEMBL19463533 0.81 PTPN1 (0.62) PTPN1SLCO2B1ABCG2ACHEKDM1A
SCHEMBL19004052 0.80 ESR1 (0.65) PTPN1SLCO2B1ABCG2ACHEKDM1A
SCHEMBL27161054 0.76 SLCO2B1 (0.69) PTPN1SLCO2B1KDM1ASYNJ2HPGD
SCHEMBL29369929 0.76 SLCO2B1 (0.69) PTPN1SLCO2B1KDM1ASYNJ2HPGD
Neophellamuretin SCHEMBL27013455 0.74 ABCG2 (0.66) PTPN1ABCG2ACHECYP3A4MAPT
Neophellamuretin SCHEMBL30766255 0.74 ABCG2 (0.66) PTPN1ABCG2ACHECYP3A4MAPT
SCHEMBL1771703 0.73 PTPN1 (0.54) PTPN1SLCO2B1ACHEKDM1ASYNJ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 — — US claimed
EP-2858641-B1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORP (US) 2017-09-06 — — EP claimed
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2015-05-21 — — US claimed
EP-2858641-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF Corporation (US) 2015-04-15 — — EP claimed
WO-2013184884-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORPORATION (US) 2013-12-12 — — WO claimed
JP-3005423-A — — None — — JP disclosed
CN-118620789-B Lactococcus lactis and application thereof in ganoderma lucidum spore fermentation 四川大学 2025-01-28 — — CN disclosed
CN-118620789-A Lactococcus lactis and application thereof in ganoderma lucidum spore fermentation 四川大学 2024-09-10 — — CN disclosed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 — — US disclosed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN disclosed
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 — — US disclosed
US-10981084-B2 Use of coconut water as extraction solvent BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2021-04-20 — — US disclosed
EP-2003968-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF Leschot Sanhueza, Andres Antonio (CL) 2008-12-24 — — EP disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 — — WO disclosed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 — — US disclosed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 — — WO disclosed
US-6329189-B1 FOR CATALYZING REACTION BETWEEN AN EPOXY RING OF AN EPOXYSUCCINIC ACID AND PHENOLIC HYDROXYL GROUP OF FLAVONOID, OR A FLAVONOID ANALOGOUS COMPOUND TO FORM TARTARIC ACID ETHER WHICH IS USED IN FOOD AND DRUG INDUSTRY KIKKOMAN CORPORATION (JP) 2001-12-11 — — US disclosed
EP-0742012-A2 Pharmaceutical composition containing substance inhibiting HSP47 production Kureha Chemical Industry Co., Ltd. (JP) 1996-11-13 — — EP disclosed
JP-H035423-A LIPID PEROXIDE PRODUCTION-INHIBITING AGENT CONTAINING FLAVONOID ICHIMARU PHARCOS CO LTD 1991-01-11 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234918-B2 Methods for botanical and/or algae extraction ALG1, ALG8, CUTA PTPN1 4794/4885SLCO2B1 4826/4885SLC28A3 4631/4885
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 PTPN1 4141/4885SLCO2B1 4682/4885SLC28A3 4597/4885
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION ALG1, ALG8, CUTA PTPN1 4794/4885SLCO2B1 4826/4885SLC28A3 4631/4885
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS THPO, SERPINB1, SERPINC1 PTPN1 1318/4885SLCO2B1 976/4885SLC28A3 3360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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