Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 9/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745830 | 1.00 | IRAK4 (0.42) | IRAK4FAAHPNMTADRA2AADRA2B | |
| SCHEMBL4743142 | 1.00 | IRAK4 (0.42) | IRAK4FAAHPNMTADRA2AADRA2B | |
| SCHEMBL2085878 | 0.88 | FAAH (0.54) | IRAK4FAAHPNMTADRA2AADRA2B | |
| SCHEMBL30194882 | 0.80 | PNMT (0.44) | FAAHPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL308901 | 0.80 | MAPT (0.46) | IRAK4FYN | |
| SCHEMBL2731112 | 0.75 | FAAH (0.57) | FAAHPNMTFYN | |
| SCHEMBL308120 | 0.74 | ALDH1A1 (0.52) | PNMTADRA2AADRA2BADRA2CCYP1B1 | |
| SCHEMBL2060177 | 0.72 | FAAH (0.57) | FAAHPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29113473 | 0.72 | FAAH (0.57) | FAAHPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL4141990 | 0.72 | FAAH (0.57) | FAAHPNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113795-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | WO | disclosed |