Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.66 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053251 | 0.91 | PARP10 (0.68) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL1785980 | 0.86 | PARP10 (0.62) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL19024978 | 0.85 | GAA (0.58) | KMT2AL3MBTL1GAA | |
| SCHEMBL12321296 | 0.85 | L3MBTL1 (0.55) | PARP10ALDH1A1PRSS1L3MBTL1TMPRSS2 | |
| Water SCHEMBL5055924 | 0.83 | PARP10 (0.68) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL1086686 | 0.83 | PARP10 (0.72) | PARP10L3MBTL1GAA | |
| SCHEMBL27987025 | 0.83 | PARP10 (0.68) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL1977030 | 0.83 | PARP10 (0.68) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL4687732 | 0.83 | PARP10 (0.68) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL1925564 | 0.83 | PKM (0.67) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168664-A1 | 4-{3-[TRANS-HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL]PROPOXY}BENZAMIDE, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN SAME | LES LABORATOIRES SERVIER (FR) | 2012-12-13 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |