SCHEMBL4743034

SCHEMBL4743034

CC(C)(C)OC(=O)C1(OC=O)CCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
CTSK P43235 1/20 0.30
USP2 O75604 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019790 0.78 PLG (0.31)
SCHEMBL30859305 0.74 CTSK (0.30) CTSKUSP2SMN1; SMN2
SCHEMBL3525539 0.74 SMN1; SMN2 (0.43) SMN1; SMN2
SCHEMBL16234619 0.73 CYP3A4 (0.42) CYP4F2CYP4A11CTSKSMN1; SMN2
SCHEMBL22927448 0.71 DGAT1 (0.33) CYP4F2CYP4A11CTSKUSP2SMN1; SMN2
SCHEMBL7435411 0.70 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL9123239 0.70 CTSK (0.33) CTSKUSP2SMN1; SMN2
SCHEMBL22098422 0.70 CYP4F2 (0.44) CYP4F2CYP4A11
SCHEMBL28535485 0.70 CTSK (0.31) CYP4F2CYP4A11CTSK
SCHEMBL571145 0.70 CTSK (0.35) CTSKSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207528-A1 Administering derivatives of 4-(3-pyrrolidinyloxy)quinoline TAIGEN BIOTECHNOLOGY CO., LTD. (TW) 2008-08-28 US disclosed
WO-2008095058-A1 HCV PROTEASE INHIBITORS TAIGEN BIOTECHNOLOGY CO. LTD. (TW) 2008-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207528-A1 Administering derivatives of 4-(3-pyrrolidinyloxy)quinoline GLS2, SLC10A1, UGT1A1 CYP4F2 8/4885CYP4A11 58/4885CTSK 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.