Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743034 | 0.78 | CYP4F2 (0.32) | — | |
| SCHEMBL7972576 | 0.75 | PLG (0.37) | PLGPLATLMNA | |
| SCHEMBL8597693 | 0.72 | — | — | |
| SCHEMBL8145030 | 0.71 | DGAT1 (0.35) | — | |
| SCHEMBL6673585 | 0.70 | NAMPT (0.30) | — | |
| Hydrochloric Acid SCHEMBL8596533 | 0.69 | DPP4 (0.34) | — | |
| SCHEMBL24693734 | 0.69 | GPR119 (0.55) | GPR119 | |
| SCHEMBL28958600 | 0.68 | PLG (0.42) | PLGPLATLMNA | |
| SCHEMBL13668662 | 0.68 | PLG (0.42) | PLGPLATLMNA | |
| SCHEMBL4483887 | 0.68 | KMT2A (0.38) | PLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763016-B1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | AXYS PHARM INC (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5656660-A | AMINE OR GUANIDINE GROUP-CONTAINING TRYPTASE INHIBITOR | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |