SCHEMBL4743115

SCHEMBL4743115

CC(=O)CC(=O)Nc1ccccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.60
KMT2A Q03164 7/20 0.56
GAA P10253 5/20 0.56
MAPT P10636 4/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
MEN1 O00255 5/20 0.54
RAB9A P51151 3/20 0.54
PKM P14618 1/20 0.54
NPC1 O15118 2/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
TP53 P04637 1/20 0.52
ALDH1A1 P00352 3/20 0.51
HPGD P15428 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912340 0.88 MAPT (0.58) KMT2AMAPTKDM4EMEN1RAB9A
SCHEMBL13416408 0.88 KDM1A (0.68) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL14817490 0.83 KMT2A (0.65) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL968912 0.82 CA1 (0.64) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL11037731 0.82 MAPT (0.53) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL860003 0.82 KDM1A (0.57) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL4361189 0.82 KDM1A (0.62) KDM1AKMT2AGAAMAPTKDM4E
SCHEMBL30065998 0.81 RAB9A (0.67) MAPTRAB9APKMNPC1LMNA
SCHEMBL382223 0.81 RAB9A (0.67) MAPTRAB9APKMNPC1LMNA
SCHEMBL17993533 0.81 KDM1A (0.70) KDM1AKMT2AGAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
CN-100390236-C Method for preparing tetrazo pigment TOYO INK MFG CO (JP) 2008-05-28 CN disclosed
EP-1146088-B1 Method of producing disazo pigment TOYO INK MFG CO (JP) 2003-07-02 EP disclosed
US-20010041793-A1 Method of producing disazo pigment TOYO INK MFG. CO., LTD. (JP) 2001-11-15 US disclosed
CN-1317517-A Method for preparing tetrazo pigment TOYO INK MFG CO (JP) 2001-10-17 CN disclosed
EP-1146088-A1 Method of producing disazo pigment Toyo Ink Manufacturing Co. Ltd. (JP) 2001-10-17 EP disclosed
US-6303762-B1 COUPLING A TETRAZO BENZIDINES AND A MIXTURE OF N-PHENYLACETOACETAMIDES TOYO INK MFG. CO., LTD. (JP) 2001-10-16 US disclosed
US-5328907-A Treatment of allograft rejection in mammals and antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1994-07-12 US disclosed
US-5108999-A For treating inflammation, autoimmune disease or allograft rejection in mammals SYNTEX (U.S.A.) INC. (US) 1992-04-28 US disclosed
US-5001124-A 4-isoxazolecarboxamide derivatives SYNTEX (U.S.A.) INC. (US) 1991-03-19 US disclosed
EP-0096795-A2 N-aryl pyridones, their preparation and use BAYER AG (DE) 1983-12-28 EP disclosed