Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726066 | 0.80 | CYP2D6 (0.43) | — | |
| SCHEMBL4725612 | 0.68 | TSHR (0.33) | TSHR | |
| SCHEMBL25009948 | 0.65 | TSHR (0.42) | TSHR | |
| SCHEMBL3923412 | 0.64 | KCNA3 (0.38) | — | |
| SCHEMBL6682974 | 0.63 | TSHR (0.59) | TSHR | |
| SCHEMBL23205864 | 0.63 | TSHR (0.59) | TSHR | |
| SCHEMBL27458230 | 0.63 | TSHR (0.59) | TSHR | |
| SCHEMBL25167464 | 0.63 | KDM4E (0.33) | TSHR | |
| SCHEMBL4419612 | 0.62 | GABRA1 (0.41) | TSHR | |
| SCHEMBL535657 | 0.62 | GABRA1 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109286-A1 | METHODS FOR TREATING COGNITIVE DISORDERS USING 1-ARYL-1-HYDROXY-2,3-DIAMINO-PROPYL AMINES, 1-HETEROARYL-1-HYDROXY-2,3-DIAMINO-PROPYL AMINES AND RELATED COMPOUNDS | ALLERGAN, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008109287-A1 | METHODS FOR TREATING COGNITIVE DISORDERS USING 1-BENZYL-1-HYDROXY-2,3-DIAMINO-PROPYL AMINES, 3-BENZYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS | ALLERGAN, INC. (US) | 2008-09-12 | — | — | WO | disclosed |