SCHEMBL4743346

SCHEMBL4743346

Cc1cccc(C(=O)N=C=O)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CYP3A4 P08684 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 2/20 0.40
TRPA1 O75762 2/20 0.40
MEN1 O00255 2/20 0.40
CYP2C9 P11712 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
AKR1B10 O60218 1/20 0.40
ABCB11 O95342 1/20 0.40
DHFR P00374 1/20 0.40
MPO P05164 1/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM1 P11229 1/20 0.40
AKR1B1 P15121 1/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4936719 0.85 ERCC5 (0.46) KMT2AHPGDNPC1RAB9ATSHR
SCHEMBL27533336 0.84 TSHR (0.45) CYP3A4HSD17B10KMT2ALMNATRPA1
SCHEMBL5824864 0.84 ESR1 (0.41) ESR1ESR2CYP3A4HSD17B10KMT2A
SCHEMBL6424083 0.82 KAT6A (0.41) CYP3A4HSD17B10KMT2AMEN1CYP2C9
SCHEMBL28088474 0.81 CYP3A4 (0.35) CYP3A4HSD17B10KDM4EALDH1A1HPGD
SCHEMBL28358167 0.80 CA12 (0.41) HTT
SCHEMBL10637292 0.79 L3MBTL1 (0.38) CYP3A4HSD17B10KMT2ATRPA1KDM4E
SCHEMBL3395153 0.78 ALDH1A1 (0.42) HSD17B10KDM4EALDH1A1HPGDMPO
SCHEMBL27885149 0.77 ESR1 (0.45) ESR1ESR2CYP3A4HSD17B10KMT2A
SCHEMBL34472768 0.76 NR4A1 (0.38) CYP3A4HSD17B10KMT2AMEN1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111320812-A Resin protective film material and preparation method thereof 昆山新博皓薄膜电子材料有限公司 2020-06-23 CN claimed
CN-109306095-A Toughening asphalt modifier, toughening composite modified asphalt, asphalt and preparation method thereof 上海仁聚新材料科技有限公司 2019-02-05 CN claimed
CN-108822403-A A kind of plastics package composite material and preparation method 罗国球 2018-11-16 CN claimed
CN-108517579-A The preparation method of easy dyeing polyester fiber 佛山市瑰栗服装材料有限公司 2018-09-11 CN claimed
CN-108385199-A A kind of easy dyeing polyester fiber 佛山市瑰栗服装材料有限公司 2018-08-10 CN claimed
CN-108117688-A A kind of low smoke halogen-free environment-friendly cable and preparation method thereof 江苏河阳电气有限公司 2018-06-05 CN claimed
CN-104559174-B A kind of preparation method of non-reinforcing halogen-free flame-proof nylon 66 having 北京科方创业科技企业孵化器有限公司 2016-08-31 CN claimed
CN-104610735-B A kind of preparation method of intumescent non-reinforcing halogen-free flame-retardant nylon 6 北京科方创业科技企业孵化器有限公司 2016-08-10 CN claimed
CN-113717646-A Die bonding film and dicing die bonding film 日东电工株式会社 2021-11-30 CN disclosed
CN-111320812-A Resin protective film material and preparation method thereof 昆山新博皓薄膜电子材料有限公司 2020-06-23 CN disclosed
CN-110128820-A A kind of timing chain guide rail and its preparation process 上海瀚通汽车零部件有限公司 2019-08-16 CN disclosed
CN-109096637-A High-impact weatherability PVC/ABS/PMMA alloy plastic and its preparation 宁波蒙曼生物科技有限公司 2018-12-28 CN disclosed
CN-108822403-A A kind of plastics package composite material and preparation method 罗国球 2018-11-16 CN disclosed
CN-207477039-U A kind of fire-fighting protective helmet 廖瑞武 2018-06-12 CN disclosed
WO-2004022619-A1 SILICONE MODIFIED POLYUREA REACTAMINE TECHNOLOGY, LLC (US) 2004-03-18 WO disclosed
US-20040054112-A1 Silicone modified polyurea REACTAMINE TECHNOLOGY, LLC 2004-03-18 US disclosed
US-6271333-B1 (A) AN ORGANIC POLYMER HAVING AT LEAST ONE REACTIVE SILYL GROUP IN THE MOLECULE, (B) A COMPOUND HAVING AT LEAST ONE ISOCYANATE (NCO) GROUP BONDED TO SECONDARY OR TERTIARY CARBON IN THE MOLECULE, AND (C) A LATENT CURING AGENT. THE YOKOHAMA RUBBER CO., LTD. (JP) 2001-08-07 US disclosed
US-6221998-B1 One-pack type moisture-curable composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2001-04-24 US disclosed
EP-0985693-A1 ONE-PACK TYPE MOISTURE-CURABLE COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2000-03-15 EP disclosed
US-5239032-A Heterofunctional macromer compound, its preparation and polymer derived therefrom NIPPON PAINT CO., LTD. (JP) 1993-08-24 US disclosed