Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 15/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739923 | 0.82 | GAA (0.48) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL23200078 | 0.72 | ALDH1A1 (0.51) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL9547640 | 0.71 | GAA (0.72) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL4742481 | 0.70 | LMNA (0.51) | ALDH1A1ALOX15MEN1KMT2AHTT | |
| SCHEMBL6505186 | 0.69 | GAA (0.57) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL4683620 | 0.68 | MEN1 (0.59) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL12858748 | 0.66 | ALDH1A1 (1.00) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL5048583 | 0.66 | GAA (0.47) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| Benzene SCHEMBL29129490 | 0.66 | GAA (0.58) | MAPTALDH1A1HSD17B10ALOX15GFER | |
| SCHEMBL418428 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095058-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO. LTD. (TW) | 2008-08-07 | — | — | WO | disclosed |