Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243740 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 | |
| SCHEMBL30602600 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 | |
| SCHEMBL3314110 | 0.85 | L3MBTL1 (0.62) | SMN1; SMN2POLBL3MBTL1ALOX15ALDH1A1 | |
| SCHEMBL29860055 | 0.85 | L3MBTL1 (0.62) | SMN1; SMN2POLBL3MBTL1ALOX15ALDH1A1 | |
| SCHEMBL4744580 | 0.85 | RAB9A (0.77) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL7607595 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 | |
| SCHEMBL2947235 | 0.84 | ALDH1A1 (0.63) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 | |
| SCHEMBL22175599 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBL3MBTL1HPGDNPC1 | |
| SCHEMBL5892980 | 0.81 | NPC1 (0.55) | SMN1; SMN2POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL3316286 | 0.81 | L3MBTL1 (0.55) | SMN1; SMN2POLBL3MBTL1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |